Why did you choose the DHA/EPA ratio of 2:1?

We are pleased to offer you a summary nutritional science perspective on the topic of the DHA/EPA ratio. We have opted for a supplement with a focus on neuroprotective, immunomodulation an metabolic effects.

The favorable ratio between docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) can vary depending on the specific health outcomes or physiological effects being targeted. Research has investigated various DHA/EPA ratios in different contexts, including their impacts on growth, immune response, disease resistance, and their association with the risk of cardiovascular diseases in humans as well as animals.

There is a scientific tendency to suggest that a DHA/EPA ratio of 1:1 or 2:1 offers benefits for brain health, specific health-promoting lipid profiles, and immunomodulation. Considering that 60% of the brain's dry weight consists of DHA, this logic becomes apparent.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563911/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372293/

For a cardiovascular-focused approach, a DHA/EPA ratio of 1:2 is advocated.
https://www.sciencedirect.com/science/article/pii/S0965229921000030

https://www.sciencedirect.com/science/article/pii/S2666602222000659 

In summary, while the optimal DHA/EPA ratio may depend on specific health outcomes (https://www.casi.org/node/948), evidence suggests that balanced intake of these essential fatty acids is crucial for supporting overall health. The studies mentioned above highlight the complexity and importance of DHA and EPA ratios.

Here, we also want to mention that the ratio of arachidonic acid (AA) to DHA as well as to EPA (DHA/AA or EPA/AA) plays a significant role from a medical perspective, just as the DHA/EPA ratio does.